I fixed a friends computer yesterday. It was BSODing on startup every boot. It turned out something was up with his Windows partition, the Windows install/rescue CD could not read it, and neither could the installed OS. So I booted a Linux LiveCD, backed up all the data, deleted the partition, and recreated it with the Windows install CD during installation.
I boot it up, and there is no C: drive. The drive that was formerly C: is now E:. If I plug in a flash drive, that becomes the C: drive (the CD drive is still the D: drive).
Is there any problems that will be caused by not having a drive under C:? i.e. Any programs hardcoding it into their filepaths, or similar problems?