We recently changed out a computer from Windows XP to Windows 7. I installed the SmartBoard drivers, made sure we connected to the SmartBoard just fine, and then tested it. After each button press that made a sound go through the SmartBoard speakers, the SmartBoard disconnects and goes through the Windows hardware discovery again. It took me a while to narrow it down to this, but I confirmed it by playing sound through a different set of speakers and I didn't have the problem.
This is connected through a USB extension. I have reseated the USB and cat5 connections on the extenders, moved to a different USB port, updated the firmware and drivers, uninstalled the drivers from the new computer and installed the old drivers, and connected the SmartBoard through a powered USB hub. I searched around online, but SmartTech doesn't have a troubleshooting guide that even comes close to this, and none of the forum posts I could find seemed relevant.