I have about 8gb of e-mail from about 10 years. I have my structure organized into a lot of folders. I am on 10.6.2, 8gb RAM and a SSD drive.
I am on OS X and using Apple Mail. It works ok. Generally not as fast as I would like.
I have used Entourage in the past and is just slow and bloated. I have had a lot of database issues.
I have used Evolution on Linux before and been happy.
I have tried Sylpheed and I dont recall why I did not like it.
Thunderbird has always been slow and quirky for me.
Eudora is dead. (except crappy sponsored mode)
What are options for fast e-mail clients that have advanced filtering and can deal with a large amount of e-mail?
Anything MySQL driven?