Two different slide designs in a single PowerPoint presentation

Question

Is it even possible to do that? If so, what's the easiest way to achieve this?

Answer 1

If you wish to change the design of a particular slide:

1. Select the slide you wish to modify by clicking on it in the Slides view.
2. Select the Format menu > Slide Design.
3. Choose the design you would like to use from the task pane by selecting the drop down arrow that appears when you hover your mouse over the preview slide.
4. Select Apply to Selected Slides.

Answer 2

Just tried it on Powerpoint 2010. If you right click the theme you should be able to apply it to the selected slides instead of all of them.

in 2003 if you are looking at the slide designs an arrow should pop up on the left side of the design you have hilighted. click that and it should give you the same option.