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My wife has a 17" Macbook pro with a Wacom tablet and occasionally the trackpad button machine will all of a sudden stop responding.

A reboot will fix the problem, but does anyone have an idea what is causing the problem, is it a bug in the Wacom driver?

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If you plug in an external mouse does that stop responding too? Does it ever stop responding without the Wacom tablet? – Mike McQuaid Jul 27 '09 at 12:05
up vote 1 down vote accepted

The cause has been found. There was a loose connection in the USB cable within the tablet which was causing the entire USB subsystem to go nuts.

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