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Regardless of whether I start the uninstall from the Add/Remove Programs applet or from the original setup executable, I always get this exception on startup:

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How can I uninstall Expression Studio 3?

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can you reinstall it first? ensures all the files are in pristine condition (for deletion). – jay Apr 29 '10 at 22:33
Starting setup.exe causes the same exact error you are seeing on the screenshot. – AngryHacker Apr 30 '10 at 1:01

Personally I would delete the files, all reg entries by searching, then disable/remove services and any startup objects using msconfig or regedit :)

Edit :

Before that you should try and advanced uninstaller

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