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I went to open Outlook 2007 on my Windows 7 32bit machine and it came up with this error:

Cannot start Microsoft Office Outlook. Cannot open the Outlook window. The set of folders cannot be opened. The information store could not be opened.

I have deleted and created a new profile in Control Panel > Mail but it still doesn't want to work properly but it still comes up with this message.

Thanks in advance.

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4 Answers

up vote 1 down vote accepted

Just had it happen to me this morning. (Win7 x64, Outlook 2007). The message can be caused by a number of issues like a compatibility setting or a corrupted outlook profile file. In my case, I had to run the following at a command prompt:

Outlook.exe /resetnavpane

The technical issues surrounding the Navigation Pane can be found at Microsoft's Support site KB2022778.

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Have you tried safe mode?

a) Hold Ctrl and click Outlook from start menu


b) "Outlook.exe /safe" from command prompt

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Yep I tried that but it came up with the same thing. I managed to sort it. Thanks anyway –  Dean Perry Jun 9 '10 at 13:49
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Have sorted it. Changed the .pst in Control Panel > Mail and created a new default pst file and it seems to be working fine for some reason.

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I tried hard to fix it but it not work for me. Then I did this and it worked for me


  1. Uninstall Program Microsoft office 2007
  2. restart
  3. Install new Microsoft office 2010
  4. Set new outlook again
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