Less flexible than screen are nohup and disown.
nohup is a program, and you have to start the long running jub with it like this:
$ nohup longjob --options-for-longjob
it will cause your long job to run in the background and not attached to any terminal (which means that you won't get any output from it on the screen and won't be able to direct input to it from the keyboard)
disown is a bash builtin that can disconnect a long running job after you've started it. My bash man page says
disown [-ar] [-h] [jobspec ...]
Without options, each jobspec is removed from the table of
active jobs. If the -h option is given, each jobspec is not
removed from the table, but is marked so that SIGHUP is not sent
to the job if the shell receives a SIGHUP. If no jobspec is
present, and neither the -a nor the -r option is supplied, the
current job is used. If no jobspec is supplied, the -a option
means to remove or mark all jobs; the -r option without a job-
spec argument restricts operation to running jobs. The return
value is 0 unless a jobspec does not specify a valid job.