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My NexStar External hard Drive Enclosure was originally set up for a PC. What can I do to make it work with a Mac?

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Go to Applications => Utilities => Disk Utility, then re-initiialise the drive in Mac format (HFS Extended). Obviously this will erase any data currently stored on the disk, so you should back this up first if it is needed.

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Doing this will wipe all data on it. – Daniel Beck Jan 27 '11 at 18:23
+1 for mentioning the data loss – Joe Taylor Jul 14 '11 at 11:26

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