jv16 PowerTools 2010 - Registry Find and Replace
The Registry Find and Replace tool allows you to find and replace data from the registry. The degree of flexibility and safety of use will make this tool invaluable to you.
The feature is especially useful when fixing the registry after a changed hard drive letter. For example, you have purchased a new hard drive and you have moved your C:\Programs directory to D:\Programs. Of course, none of the programs actually work since the registry still contains the old path at C:\ drive. Fixing the program with the Registry Find and Replace takes only a few clicks: search for "C:\Programs" and replace it with "D:\Programs".

Why this feature stands apart compared with its competitors
- Can search with many search words at a time
- Can find registry items based on their last modification date
- Supports searching with wildcards, Perl Regular Expressions and Artificial Intelligence
- Safe to use, as the backup feature is activated by default
Reg Organizer 5.10
License: Shareware $29.95
Requires: Win7/Vista/2K/XP
Reg Organizer® is an extensive and extremely powerful set of registry tools required for effective system registry management. This software lets you view, edit and safely clean the registry. It allows to preview the registry files you want to import (including the ability to preview files directly from Windows Explorer). Includes registry cleaner, which will safely compact, repair and optimize the registry.
With Reg Organizer you can thoroughly search the registry to find all the keys related to a certain application - Reg Organizer does this job quicker and better than other similar programs. Other Reg Organizer features include the ability to find and replace the registry entries, automatic registry cleanup, Disk Cleanup tool, access to many undocumented Windows features. Plug-in expandability gives unlimited possibilities of third party enhancements.
RegEditX 2.0
License: Freeware
Requires: Win All
RegEditX (Registry Editor Extensions) is freeware that enhances the Windows Registry Editor. If you edit the same keys repeatedly, this is for you! New buttons activate frequently used commands, and a combo box stores a history of visited keys and allows quick navigation back to them.

The keys are saved across sessions and available the next time you use the Registry Editor.
Registry Commander 1.04.3054
License: Freeware
Requires: Win All
An enhanced registry editor, which can do a lot of neat stuff that the Windows Regedit can't.

Use this application as a replacement for the registry editor that comes with windows (REGEDIT.EXE).
Registry Commander can do what all other registry editors can't such as cut/copy/paste, advanced search, change value type (string => binary), bookmark of keys and values, support of other types than just strings, dword and binary values.
A thing I never understood is why no registration database editors showed the size of the value data, this is properly one of the things that made me create this application!
Reg
OPEN SOURCE (great search, but no replace option, sorry...)

Check out these features:
Efficient interface: On some platforms, Reg is faster than RegEdit.
Bookmarks: More recent versions of RegEdit implement Favorites, but Reg uses a more convenient bookmark box attached to the main window. Of course, Reg also works on older versions of Windows, where RegEdit has no Favorites featuers.
Background search: Searches are conducted in the background, allowing the user to continue working with the registry.
Regular expression search: Weed out those pesky, hard-to-find registry keys using a regular expression search.
Partial search: Limit search scope to only a sub-tree of the registry. Great for searching, for example, HKEY_CURRENT_USER\SOFTWARE!
Search results: Search hits are collected in a pane on the main window, Allowing user to get an overview of the search hits, scan the list, jump back and forth between hits, etc.
Tired of stepping through a registry search? This is the feature for you!
Multi-delete from search results: Registry need a cleaning? Do a search and then delete en masse from the results.
Export and import: Can export standard version 4 registry files, and import version 4 and 5 registry files. (Unicode not supported for v5 files).
Full Windows XP Visual Style support.
For more:
http://majorgeeks.com/downloads15.html