Which antivirus software on Linux is most popular?
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Probably ClamAV, but you don't need that for desktop usage. The typical reason ClamAV or other AV software gets installed to Linux/Unix is that someone needs to protect all those Windows boxes in the network -- ClamAV usually scans the file shares, e-mails and so on for Windows viruses.
If you're paranoid, you most likely want to scan your Ubuntu with chkrootkit and/or rkhunter instead, and setup AIDE or some other intrusion detection software. But for most of us that's really overkill (for now, at least).