Somewhere between 50% and 70% of the times I start my computer, I get the following bluescreen:
STOP: c0000218 {Registry File Failure}
The registry cannot load the hive (file):
\SystemRoot\System32\Config\SOFTWARE
or its log or alternate.
It is corrupt, absent, or not writable.
I recently had to lower the memory clock from 1066MHz to 800 MHz because of data corruptions (random crashes from normal usage, failing shaders and textures in games, screen corruption, things like that...); it's now running slower than the official specification and also has a much slower stepping. I also had to reset the bios to its default values. I've got a Republic of Gamers board with Nvidia chipset and AMD processor.
Once Vista runs, the system seems to be perfectly stable.