I have a large number of different passwords on different sites. There are some I re-use regularly on sites that I consider low-risk; unfortunately, sometimes I leet them differently at various times. Important sites, such as banking, email have unique passwords. I also allow my browser to remember my password on sites I consider safe, or for which the consequence of a password attack would be minimal.
I don't trust keeping important passwords on my computer, no matter how well encrypted, since reading an article at Microsoft that 128-bit PK encryption can be broken in a few hours by a powerful computer.
I keep my passwords in a spiral book -- that seems the only safe place to me, so long as access to the book is protected. In an office, I would keep the book in a locked file-cabinet, &/or off-site. When I am travelling away from home, book goes with me, in a separate piece of luggage from my laptop.
I am convinced that the best security is physical security.