Take the hypothetical scenario in which an individual (say, a political dissident in a police-state) would need to achieve optimal or near-perfect security for the safe storage and transmission of data.
We make the following assumptions:
Every intermediary between you and the parties you communicate with have the intent of intercepting your transmissions, and will use the best methods of cryptanalysis publicly known to obtain your data.
The physical security of your computer cannot be assured.
Coercion and legal obligation can be used against you to surrender information (keys, etc.).
Using open-source software (given the uncertainty of commercial solutions -- we do not know if a given application is subject to security flaws or has in itself a method of subversion), which software would you use to go about this? By which other methods might you achieve a greater degree of information security?