I cannot figure out for the life of me if a National Instruments PXIe card (such as this) will fit and work correctly in a standard PCIe slot. Their website is not helpful at all in answering this question. It seems to be hinted at that a chasis (like this) is required to operate any PXIe cards but I can't tell if it's just something extra they want to sell you.

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That card will not work in a PCIe slot. You will need to purchase a PXI chassis. It probably is them just wanting to sell you something (by using a proprietary connector), but not something you can get out of.

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Thanks for the help! So frustrating – Nick Aberle Jun 14 '11 at 20:00
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No, 2 different standards. They are not interchangeable

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It is electrically compatible, but physically incompatible. You may be able to find an adapter for it, but I have no clue where.

PXIe ... is electrically identical to the PCIe specification, except it uses the Euro (VME) card 3U/6U format with 2mm connectors.

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Europe always has to do it differently... SCART, anyone? – ta.speot.is Aug 2 '11 at 22:21
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According to this page here, you will basically need a chassis because PCIe does not work with PXIe, although, according to this picture and the previously linked page, when you get their chassis, it is backwards-compatible with PCIe. enter image description here

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