There's no hard and fast way to totally disable a program - every program is different, and in any case, reinstalling it probably 'fix' whatever you did to disable it.
On the other hand you COULD set up the computer as you like it, and use a standard account (disabling what you don't want with autoruns )and use 'guest mode' to prevent changes from happening. You can also remove execute privileges to the folders with the software you want (rightclock, properties, security tab), to this account.
Unlike messing with things at a low level, should you need to undo these changes, it should be trivial, and a guest moded user account will be able to do almost nothing.