CSRSS is the "Client/Server Run-Time Subsystem" and it's the user mode part of the system (in contrast to the Kernel mode, see link for more explanation).
According to this site:
CSRSS is responsible for console windows, creating and/or deleting threads, and implementing some portions of the 16-bit virtual MS-DOS environment.
There's also a Wikipedia entry on it.
LSASS is the "Local Security Authentication Server". Here's what it does:
[...] is responsible for enforcing the security policy on the system. It verifies users logging on to a Windows computer or server, handles password changes, and creates access tokens. It also writes to the Windows Security Log.
I am not a Windows expert, but as you can see, those two processes are essential for the operation of Windows and I wouldn't wonder if they need constant reads/writes from the hard disk to perform their tasks.
Note that those two files are often target of viruses, who disguise themselves as the process.