I am using a Razer Deathadder 3500dpi mouse and in 10.7, the vertical tracking is inverted at the EFI login window. I have FileVault enabled, so this is the password entry screen immediately after boot before any drivers from the encrypted system partition are loaded. I tried installing the official Razer driver (currently 3.0.0) with no success. I have since uninstalled the driver and am sort of stuck.
Additionally, I am seeing problems with assigning the "Show Desktop" shortcut to any mouse button in System Preferences > Mission Control. No matter which button I assign it to it will not work. I never had a problem with either of these in 10.6.
EDIT: The "Show Desktop" shortcut is temporarily solved by turning off the shortcut, logging out, then logging back in and turning it back on (after each boot).