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In OS X, you just assign Cmd or ctrl + mouse scroll for zooming in. This works anywhere, in any app.

Windows 7 also has a nice magnifier, and has some hotkeys:

Magnifier keyboard shortcuts

The following table contains keyboard shortcuts for working with Magnifier.

Windows logo key + Plus Sign or Minus Sign    Zoom in or out
Ctrl+Alt+Spacebar Preview the desktop in full-screen mode
Ctrl+Alt+F    Switch to full-screen mode
Ctrl+Alt+L    Switch to lens mode
Ctrl+Alt+D    Switch to docked mode
Ctrl+Alt+I    Invert colors
Ctrl+Alt+arrow keys   Pan in the direction of the arrow keys
Ctrl+Alt+R    Resize the lens
Windows logo key + Esc    Exit Magnifier

... but I want to use the mouse for zooming in and out like in OS X. Is that possible?

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You cannot use ctrl+scroll for zooming because it's already assigned to desktop/explorer icon zooming – Lưu Vĩnh Phúc Sep 17 '13 at 6:33

Try ZoomIt for the zooming (free from SysInternals). I prefer ZoomIt more than Windows Magnifier. It even allows me to draw on the screen -- perfect for presentations. The thing is, you'll still have to use the keyboard to activate ZoomIt; zooming in and out can be done using the mouse wheel.

The only way to get exactly -- at least based on my knowledge -- what you want is to use AutoHotKey script that traps the Ctrl+Wheel events and emulate WinKey+Plus Sign or WinKey+Minus Sign key press.

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