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Is there any way to prevent this? I've disabled the iTunes Helper Login Item but iTunes will still start automatically when I connect my Bluetooth Headphones.

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Couple of related forum entries. Haven't seen a fix yet -- weird issue. – slhck Jul 28 '11 at 19:37
You may need to uninstall iTunes. Many other people have had this problem for years, and none have found solutions. very sorry. – wizlog Jul 28 '11 at 20:20
For me it just started happening in Lion. I've been using BT headphones since Leopard. – sirlancelot Jul 28 '11 at 22:48
up vote 7 down vote accepted

It is completely stupid and seemingly unrelated but it works:

In the CDs and DVDs preference pane disable iTunes to launch inserted for Audio CDs

your headset is an audio cd you know ;-)

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Definitely stupid, but works! Thanks – sirlancelot Sep 4 '12 at 20:47
Thank you! OSX does some boneheaded things. – Chris Nicola Dec 6 '12 at 23:28
Can't do this in Mavericks. :( – Noldorin Jan 21 '14 at 21:14

What I did is renaming itunes using

sudo mv /Applications/ /Applications/

But It does ask where is iTunes when you connect the headset. At least after moving the window around, it doesn't nag me anymore.

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Probably the only around this for now... – sirlancelot Aug 31 '11 at 23:43
In addition to renaming itunes, you can create a "do nothing app" in its place called On AskDifferent, here are complete steps to solve this annoying issue. – Joe Fletcher Aug 9 '13 at 18:44

I figured this out on Mavericks. I did five steps:

Rename the to

Open a blank AppleScript Editor and save a blank window in the Applications folder as an application type (not the default script type) as

Remove the iTunesHelper from system preferences > users > login items

Connect to the bluetooth speaker it will ask you where is iTunes located? Click browse and point it to the

(iTunes will still launch when you connect to a bluetooth speaker)

In Finder go to Applications and show package contents on Inside the MacOS folder there is a unix script called iTunes, i right clicked get info and changed the name to iTunesclosed.

With the first three steps, iTunes still opened whenever I connect to my bluetooth speaker. This last step prevented iTunes from opening.

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