can I have Mac Mail using me.com send from my business email address instead of me.com address?
Annoying that I use me.com to sync between all of my apple devices but my work emails come from my me.com account.
In the Mail's account information/email address box, add any extra addresses you might want to send from as a comma-separated list. Thereafter, Compose windows' From address box will have a dropdown listing each of those addresses.
I use this with another IMAP provider but I don't see any reason why it would be provider sensitive. See this link