Is there any way to execute a command from
notepad++ and have the results piped back into the program in a new tab?
If your program outputs plain text and you can run batch files...
For more flexible, you can install the NppExec plugin. The easiest way to install it is through the built-in Plugin Manager:
After that, the fun begins. This tutorial is a good starting point on how to use this powerful plugin: https://micksmix.wordpress.com/2009/09/24/format-your-perl-scripts-using-perltidy-and-notepad/
It should work with any command-line utility that outputs text to the console.