I run :!node app.js from inside Vim and after hitting ctrl-c to end it, the bottom half of the window is blank. Even hitting ctrl-L to refresh doesn't work.
This has happened on both OSX 10.6 and 10.7, and with the default OSX vim as well as the latest stable version which I compiled (vim 7.3). And I've tried it with iterm, iterm2, and terminal.app.
Probably not Node related, but if I run a command like "!ls" or "!cat %" (to echo current file), they work fine.