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I'm looking for some free editor for Windows that I can use to adjust levels and curves on 16-bit TIF files. Do GIMP and/or Paint.NET support 16-bit depth? What are my options?

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I believe Paint.NET is limited to 8-bits per channle but I don't have a reference for that.

Mainstream Gimp is limited to 8-bits per channel.

Variants of Gimp used by the film industry have greater bit-depth

Film Gimp has vast dynamic range: 16-bits per channel (64-bit RGBA)

Film Gimp is also known as CinePaint

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Check out ImageJ from Nat Inst of Health (USA). Java client program that is very powerful but not super user friendly.

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