I've noticed when doing a backup or even just logging onto the WHS console, my MBP will lose it's wireless connection usually about once a session. Any idea why?
Here's one rule of thumb: set the MTU on your MBP and/or the router to 1490, or maybe even little less.
The maximum is 1500 and it's usually the default on Mac and some routers. This may bring some problems eventually. Here is a nice guide on how to optimize it. I hope that link doesn't break too soon. :P