I am changed the toolbar and window (like solution explore, properties windows etc.) arrangement settings i.e arrange as per my conventions.
Now I am close the vs2010 and next day I open the vs2010 then my setting lost and this things happen some time not always. i.e. some times saved and some times not saved.
e.g. I create macros, I create new toolbar and arrange my macro on my new toolbar and rename the display name of the macro.
Now I close vs2010 normally and reopen then I lost the my renamed macro it set the original name.
After reopen the visual studio I get this: