This has been a reoccurring issue for me, pretty much since I've owned this laptop (an ASUS G60JX.) Sometimes, the cursor will stop working properly and instead tend toward the top right of the screen. Basically, sometime into my usage (maybe after a couple hours) the touchpad will inevitably begin to malfunction, where it has confusing patterns of pushing the mouse cursor toward the top right of the screen. In addition, certain features (like momentum) seem to quit working entirely. It makes using the cursor extremely difficult.
I've been having this issue across very many drivers. Pretty much as soon as multitouch came into the mix, although I don't believe multitouch has anything to do with it. It appears that, in the state of malfunction, it doesn't matter how you touch the touchpad, but where you touch it. Certain regions do not seem to trigger the cursor to move to the top right corner. In fact, no specific region seems to, but some areas do so more often than others.
The issue can be resolved temporarily by putting the computer into sleep mode and awakening it. I have found no way to recreate this success without sleeping the computer or rebooting. Disabling and re-enabling the touchpad device does not do anything to resolve the problem.
This issue does not affect my WACOM tablet nor any USB mice, and can be resolved (not to my satisfactory) by uninstalling the touchpad drivers. I'm looking for a solution, or at least a workaround that doesn't require sleep mode.