This is a followup to How to make the first page of a PDF display by itself and the succeeding pages display two-up - how do I get Acrobat X on Windows 7 to print a file with a title page correctly in two-up mode so that the title page starts on the right half of the paper? The pdf in question is the LuaTeX manual.
Prepend an empty page in front of the manual. (You may use
I think that's the only way, as you cannot get what you ask for directly from Acrobat X on Windows 7.
Create empty page with Ghostscript:
Prepend emptypage.pdf to your manual: