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I want to password-protect a few applications (not just files/folders) on Windows 7, such that, there is no change to the protected application's .exe file itself.

Since the .exe files can't be changed, "Empathy" and "Protect Exe" can't be used as they change the .exe file.

I tried using WinGuard Pro and LockThis! also but they don't work for Microsoft Outlook and some other apps (that I need).

Is it possible at all? Please help.

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Why do you want to password protect them? (If it is to only allow a limited subset of users to run them, then there are other ways.) – Richard Mar 5 '12 at 9:07
What sort of access do the users normally have on the system? Are they in the Administrators group? – Iszi Mar 5 '12 at 16:31

A computer administrator can use user account to set up permissions for access to individual applications, rather than trying to password the executable files.

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I think the OP is trying to protect the files from modification, not execution. – Iszi Mar 5 '12 at 16:30
Iszi is correct, hence “such that, there is no change to the protected application's .exe file itself.” Of course write-access can be set as well, so that should do the trick. – Synetech Mar 5 '12 at 16:55
Not going to argue over semantics. – Amicable Mar 6 '12 at 8:53

All modern applications store their data in the particular user's profile folder. The only thing you need to lock is your Windows account. That's how you use a computer properly.

If you need to lock down a kiosk PC, you can use group policy to whitelist / blacklist applications. Any other approach is pseudo security and no such "solutions" should be provided by anyone even if known.

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Also important note to this is that win+L will lock the pc. – user38331 Apr 24 '15 at 7:52

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