I experimented with Winbuilder, and after some time I noticed that I cannot resize columns in uTorrent, move bookmarks and bookmark folders in Chrome, then cannot resize columns in Comodo Programs Manager - everywhere! For example , in uTorrent, columns just froze where I left them last time. But Windows Explorer is functioning properly. Where should I search for this problem? I think this is something wrong with registry, but regular registry cleaners do not help. And I cannot even resize a columns in regedit - this is a real hell!
Start by running the Windows System File Checker utility sfc.exe and see if it finds a corrupt system file.
Can we assume you have used a good anti-malaware tool or two( or three) to assure it is not an infection of some sort?