I tried it for Orange Romania and the original connect software and drivers that come with the modem do not work, nor do those on the original Orange Romania website. The software actually made my computer unresponsive at one point and kept acting out all the time, while still not providing access to the internet (No device connected).
It is an issue with the new Lion kernel, which is all 64bit, and the crappy software Orange makes.
I did not manage to make it work with the Orange Internet Everywhere software, but I did follow this guy's tip http://www.sociallyinert.com/?p=9 and made it work through a new network interface in System Preferences, which turns out is a better way of connecting anyway. Works for Orange Romania and for Orange UK for sure. Feel free to add any other countries that also fit in.
In order to make it work you have to:
Telephone number: *99# Account name: orange Password: orange
And click "Connect". It may ask you to save the preferences. Choose Yes.
DONE. It should now have connected to the internet. Now anytime you connect your Huawei modem you only need to go to System Preferences > Network > Orange and click Connect.
Hope this helps.
ps. You can also put an icon in your menu bar and connect from there. For this while in System Preferences > Network > Orange - click "Show modem status in menu bar". It's now in your menu bar - it looks like a telephone - and you can connect faster.