My mind is irrevocably programmed to switch applications by hitting Tab while depressing the key immediately to the left of the spacebar. I think it's got something to do with the way the hand is positioned on the keyboard naturally and hitting any modifier key other than Alt with the thumb is quite awkward.
This has made my transition to Macs quite a bit easier than it could have been.
I now dual boot Windows 8 Release Preview and OS X Lion on my Macbook Air and it simply takes too much mental processing to have to consider the OS I am running in order to perform the correct task.
So what I intend to do is to bind the Command key (which functions as the Windows key now) to the Ctrl key so that I can comfortably save my files and close windows and whatnot, because Ctrl being usable by the thumb is fantastic, but this leaves the problem with Alt+Tab.
I will surely resort to the dead simple AutoHotKey solution but I was wondering if there is some way I can hack the registry (I have used a program called KeyTweak to set these registry settings to achieve the aforementioned Windows to Ctrl mapping) so that only Left Ctrl+Tab will fire Left Alt+Tab? (To get an actual Ctrl+Tab I could use Right Ctrl.)