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I have a file server running Windows Server 2003. Our QuickBooks company files are hosted there for multi-user network access. Everyday around 2 PM, when our accountant tries to switch between company QuickBooks files, an error message pops up saying that the network drives can't be accessed. They can't be accessed by any computer on the network. Our accountant switch files within QuickBooks multiple times a day, it's around 2 PM that the network access to shared drives on the server fails. Reboot fixes the problem temporarily.

What could be causing this?

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Is there anything in the event logs? –  Hennes Sep 6 '12 at 14:52
    
An unexpected error has occured in "QuickBooks": Returning NULL QBWinInstance Handle. This shows up in the Application log. It happens multiple times a day before and after the file sharing quits. –  staticBatch Sep 6 '12 at 15:04
    
Switching QuickBooks files does not generate this error. I just tested it. The errors happen every 20ish minutes while QuickBooks is running. They cluster in groups of 3 with the same time stamp, every 20ish minutes. –  staticBatch Sep 6 '12 at 15:16
    
I should have been more specific. Any error on the event log on the server? Esp. at the same time or in threes? –  Hennes Sep 6 '12 at 16:17

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