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I have no idea how this has happened. I am running a VM on a drive and out of nowhere all permissions on that drive seem to have somehow become corrupt.

I cannot open directories on the drive. Everything results in Access Denied.

I have tried running icacls and takeown. Both result in access denied. Any suggestions, I have used Windows for years and have never seen anything like this.

I appreciate your help in advance.

Edit:

I disabled UAC and can now access the drive - ODD. What would UAC have to do with this?

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UAC has everything to do with it. Bypassing it removes all sanity checking on the ACLs, so you are free to mess with it as you like. –  user3463 Sep 9 '12 at 16:45

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