I have Microsoft Wireless Mouse 5000 connected to USB dongle by radio, along with Microsoft's keyboard, and USB dongle is connected to KVM into "keyboard" socket.
I have mouse wheel working badly in some applications, for example in Adobe Help system which probably written in Air.
The situation is follows: if I rotate a wheel slowly, scrolling doesn't occur at all. If I rotate quickly it occurs. So in everyday work it feels like window reacts lazily, sometimes skipping my scroll commands.