The man page says this:
Host Restricts the following declarations (up to the next Host keyword) to be only for those hosts that match one of the patterns given after the keyword. If more than one pattern is provided, they should be separated by whitespace. A single `*' as a pattern can be used to provide global defaults for all hosts. The host is the hostname argument given on the command line (i.e. the name is not converted to a canonicalized host name before matching).
A pattern entry may be negated by prefixing it with an exclamation mark (`!'). If a negated entry is matched, then the Host entry is ignored, regardless of whether any other patterns on the line match. Negated matches are therefore useful to provide exceptions for wildcard matches.>
See PATTERNS for more information on patterns.
HostName Specifies the real host name to log into. This can be used to specify nicknames or abbreviations for hosts. If the hostname contains the character sequence `%h', then this will be replaced with the host name specified on the command line (this is useful for manipulating unqualified names). The default is the name given on the com- mand line. Numeric IP addresses are also permitted (both on the command line and in HostName specifications).
For example, when I want to create an SSH Config for GitHub, what should Host and HostName be respectively?