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I ran the Combofix program to check for malware and it deleted ntuser.dat from C:\programdata. Is the file necessary in that folder?

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no, don't delete. – Sathya Nov 15 '12 at 7:52
Combofix saved a backup of ntuser.dat. If I copy that back to C:\programdata, will that solve the problem? – user701510 Nov 15 '12 at 8:10
@Sathya: Sounds like it's too late... – martineau Nov 15 '12 at 11:14
Ntuser.dat in c:\programdata ? That's not a standard location of this type of file. Ntuser.dat contains user registry. So it should be fine withou it. I would try to use antivirus check before delete, but... – week Nov 15 '12 at 12:23
up vote 3 down vote accepted

ntuser.dat is the HKEY_CURRENT_USER hive for the registry.

It should be under your user folder like C:\Users\Your User Name. I thought the file deleted from C:\programdata\ is a malware or at least not for user registry.

Keep the backup and reboot. if everything works fine, don't recover the backup file.

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