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I have a Dell Latitude with windows 7. After a year of usage, the mouse clicks suddenly stopped working. It behaves like this with both the native mice, and with a USB mouse.

Left-clicks stopped working all together. Right-click sometimes work, but most of the time, it does unwanted things.

I suspect it’s some malware, so I ran AVG, SpyBot and MalwareBytes, but found nothing. I checked the mouse settings in the Control Panel applet, but I didn’t fine anything unusual.

Does anybody know what could be the problem or how to fix it?

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Does it work as expected in Safe Mode? How about if you boot to a different OS (like with a Linux LiveCD, or your Windows 7 install disk)? Did you try a System Restore? – Ƭᴇcʜιᴇ007 Dec 22 '12 at 19:28
Try Combofix – Ofiris Dec 22 '12 at 19:31
sys restore didn't help. the problem occurred also in safe mode. – golan Dec 22 '12 at 20:43
Have you tried each of the USB ports on the Latitude? Also be certain that your known-good mouse works in other machines. If it is a wireless mouse, are the batteries fresh? – Mac Dec 23 '12 at 6:20
Tried all the usb ports, and tried the usb-mouse on another machine - it worked. So the problem remains. – golan Dec 29 '12 at 4:51

System restore could be your friend. Try rolling your system back to an earlier date to see if that fixes your mouse problem.

Added: You might also try running the System File Checker.

Added: Check to see if a third-party shell extension is causing the problem. You can try disabling them using ShellExView.

Also, check whether the problem persists in safe mode. If it doesn't, then try performing a clean boot.

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thanks for the reply. tried it. didn't work. – golan Dec 22 '12 at 20:43
This didn't help, but thanks. Will be happy to hear of any other ideas. – golan Dec 29 '12 at 4:49
@golan Okay, I've added a couple additional suggestions. – Nicole Hamilton Dec 29 '12 at 7:48
Shellexview did show me some programs i didn't know were running. Disabled some - didn't help. The problem occurs also in safe mode. Any other recommendations before formatting are most welcome. – golan Dec 30 '12 at 5:37

Check for wireless devices.

I had the same problem on two different computers at the same time and they had both worked fine until . . . I powered on a wireless router.

Turned the wireless part of the router off and all returned to normal mousing :-)

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