Not to clear the data in the selection, rather to remove the selection itself. I suppose this would be equivalent to selecting a different range, such as A1..
erm, you can always use VBA to reference the worksheet and cell range?
This will clear off cells A1 to B17 in the worksheet ACME_Sales.
EDITED Edit answer to reflect edited question.
This will let VBA remove any selection on ACME_Sales and then just select the cell E2.