Several times I have gone to msconfig and unchecked SendIt from automatically starting with boot up. Several times, after a reboot, SendIt starts up and a box shows up. Am I doing something wrong or can YouSendIt override msconfig choices?
If one modifies some application start up option while the application is still running - it is easy for the application to check the setting and change it back.
Try changing the setting after you closed the application first.