I've downloaded adt-bundle-windows-x86_64. Everything work fine but if I'm focused on a xml file when I click on Run button or press CTRL + F11 or try to run from the Menu, it doesn't work.
This is a special configuration in Eclipse
You can try this:
Eclipse -> Window -> Preferences -> Run/Debug -> Launching -> Launch Operation -> Always Launch the previously launched application
Or you can use Select a .java file via Ctrl+F6 then Run the project's exec via Ctrl+F11.
I see all above ways here.