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Everytime I reboot, i need to to go the Control Panel / Mouse Properties / Pointer Options and cranck up the pointer speed. Is there a way to persist this setting?

I've had the same problem with Vista and Windows 7.

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up vote 5 down vote accepted

You could throw a batch file in your startup folder:

reg add "HKCU\Control Panel\Mouse" /v MouseSensitivity /t REG_SZ /d 20 /f

Just change the sensitivity as desired. 1 (lowest) - 20 (highest). Save as mouse.bat for example, then put it in the startup folder in your start menu.

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Doesn't work for me in Windows 7. The only thing that seems to work is by using the Mouse section of the control panel. –  Pat Jan 21 '11 at 15:39
    
@Pat you have to run it as administrator. –  John T Jan 21 '11 at 16:39
    
I have it in my startup folder, so it runs under my (admin) user on login. When I run it by right-clicking and selected 'run as administrator', it still doesn't work. –  Pat Jan 24 '11 at 15:29
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