I leave Adblock turned on for all sites by default. I allow ads on some sites. You can do this by adding an exception for a site that is allowed to show ads. This puts a site in the white list.
However, I do not know how to allow most ads on a page, but block a specific ad. I am not even sure Adblock will do this. I believe it is all or none. If a site is in the white list, it appears that all other rules are ignored.
Is there a way to allow most ads on a website, but still block specific ads?