Just trying to squeeze every drop of performance I can out of Chrome.
A user has tested Adblock vs Adblock Plus in Chrome.
He found that both extensions use around 100Mb of RAM, but the difference in CPU usage is really big.
Adblock Plus uses 30-40% CPU, while Adblock uses only 1-2% CPU.
Also a new website (without cache) opens faster with AdBlock (3 seconds / 1 second).
I only translated it into english because it's originally written in german
If you press Shift + Esc you can view the CPU/Memory usage for each extension. The best way to check the performance/resource intensity of each would be to monitor the CPU and Memory usage for each extension over a period of time with the same content open.
Earlier I had Adblock Plus installed and now I'm using Adguard. I did try Shift + Esc keys to view the Memory usage for both extensions on Chrome, but it's not working.
Through Task Manager, I witnessed that AdGuard's ad blocking software consumed 50,000+ ram and the adblock plus taking 150,000-250,000 depending upon the filters I installed.
So, in my opinion, Adguard is faster than both Adblock and Adblock plus. For your reference, please view a screenshot I uploaded here: http://www.screencast.com/t/JVGXIlFxq as the proof of my words. I hope it's gonna work!
It's worth noting that the resources in the extension process is only part of the story. A number of extensions, especially ad blockers dramatically increase the resource consumption of the per-tab process itself.
Due to how ad blockers work, this effect is often more pronounced on pages that contain lots of frames. The following page has a lot of iframes on it which exaggerates the effect greatly: https://vimcolorschemetest.googlecode.com/svn/html/index-html.html
In a quick test without any extensions, the tab process used 70 MB of ram according to Chromes task manager. BetaFish Adblocker increased this number to almost 2 gb. Tampermonkey and LastPass also each increased this value to ~500mb each when tested in isolation.
The important takeaway here is that resource consumption is often non-obvious, and that to test the effects properly you really need to test in isolation and look at the tab process resource usage, not just the extension.
That said, to answer your actual question uBlock appears to be the most lightweight ad-blocking Chrome extension designed specifically to be as light weight as possible.
If your goal is to get as much performance as possible, I encourage you to test each extension individually using a page such as the one I linked earlier to measure the effects each extension you're running has as you might be surprised at the results.