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Why do I get the below error whenever I click on a link in a message in Outlook 2007?

General Failure. The application cannot be found. 
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up vote 0 down vote accepted

Control Panel > Internet Options > Advanced > Reset Internet Explorer Settings > Reset... > Reset

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But this might change things that one wants to remain the same. – systemovich Nov 19 '09 at 12:00
At least make sure that you have a 'Default' browser set – baldy Jan 6 '10 at 12:30

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