Whenever I insert a pen drive, I am not able to open it.
Vista shows me this error:
Please insert disk into removable drive
I have tried changing the drive letter, but it didn't help.
Can you access this drive from other machines?
If the answer is no - the drive is probably damaged, or it is one of the two items I have listed below.
If the answer is yes, Can you give model details and I can look in to it - it is possible the drive has "special" features which are not Vista compatible.
I have only seen this on two occasions: