Are you interested in security or "more or less security"?
If you're interested in security (usually when you are in control of your machine), in this scenario, nothing beats NoScript IMHO. YesScript is an alternative, but:
Unlike NoScript, YesScript does
absolutely nothing to improve your
security. I believe that Firefox is
secure enough by default and that
blocking all scripts by default is
paranoia. YesScript strives to remove
hassles from your browsing experience,
rather than add them.
This is from the YesScript official add-on Mozilla's website. And I don't think "Firefox is secure by default". Blocking all scripts by default isn't paranoia. To have a really secure environment you block suspicious behaviors so they won't use a possible exploit that wasn't fixed.
If you're interested in a "more or less security" - suppose a machine with a non technical person using it - I suggest using WOT. You can try YesScript too. But remember it can be more secure.
When I started using NoScript, I thought it was a pain because EVERY website I was using, it was blocking javascripts. But you get ussed to it, and after 2 years using this extension, you get used to it.
For tech users, I don't think there's better approach then NoScript, ABP and WOT extensions together.