I've inverted the colors for everything on my Mac, which makes it much easier to read text. The only downside is the images. It would be nice if there were a way to invert only the pictures in Chrome. I've found extensions that reverse everything, but I've not seen a way to reverse images.
So to be clear, I've already inverted everything, so by inverting the images they will be reverted back.
It would be great to be able to invert Videos too, but I figure I can tackle that later. Less of a big deal.