The only thing I'm aware of so far is that you shouldn't defrag a solid state drive or that ruins the life expectancy of it. Is there anything else? What about 3rd party programs like ccleaner. I have ccleaner set to clean every time I turn my computer on. Is that bad for a ssd?
There has been a lot of disambiguation about running things like CCleaner and Defrag on an SSD. Running constant sequential writes can in theory shorten the life expectancy of an SSD. However you're only loosing days off of an life expectancy of years. The drive will outlast your use of it for sure. The thing about Defrag is it won't speed up your drive in the slightest since SSD's can read so quickly that fragmented files are no longer the issue they used to be. CCleaner will not hurt your drive in the slightest. Here's a great link for a thread from Tom's that talks about defraging an SSD.
In short I went to an SSD raid 0 in my rig two years ago and would never go back
One precaution you should take is to backup as normal Alex.
That is not to say SSDs are unreliable. Far from it. I've personally deployed and supported lots of PCs and laptops for many years and I have to say that SSDs are a joy to work with in comparison to the traditional spinning hard disks. I've yet to see an SSD fail.
Speaking to several laptop engineers however, when SSDs fail they can fail suddenly without any warning. This is unlike with the traditional hard disks where you can hear them start to make that whining scratching noise when they start to degrade, thus you have time to make a backup. So back up as normal Alex.
Hope that helps.
If you care about your SSD life time then you need to be aware that due to limited write/erase cycles number per sector the device may start dying after a few years of serious usage. From this perspective it is recommended to put the most rewritable data on the HDD. OS will run much faster being placed on SSD, of course, but OS itself has files that are rewritten often.
In Unix-like OS you can afford you to keep your home directory at any different partition. Myself have it with SSD + HDD couple. In Windows, I don't know how separate OS itself and Users or Documents and settings folders from each other.
As I said if someone cares about lifespan. Of course to get all speed purchased most writing should be on SSD.
At the time I am writing this I was also told, that