I've got a USB hub with 4 ports, and I've plugged 2 usb keyboards and 2 usb mouses. They work very fine. I've setup'ed 2 monitors too, so I was thinking about the possibility of the mouse and keyboards works independent one of another. I want two mouse pointers (I think each with different colors) and 2 keyboard cursors.
I think it a nice idea, but I don't know if this is possible... :(
PS: My OS is Windows7